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Director of Proton Therapy & Radiotherapy
Senior consultant
Singapore Institute of Advanced Medicine Holdings
Visiting consultant Icon Cancer Centre Singapore
Visiting consultant National Cancer Centre/ KK Women’s and Children’s Hospital
Click here to download her profile.
Insurance Panels:
Main panel: HSBC Life (shield), Great Eastern, Income, Prudential
Extended panel: Singlife (pre-authorisation), AIA (pre-authoristion)
Biography:
Education:
Dr Wong Ru Xin graduated from the National University of Singapore on the Dean’s list in 2009 and started residency training at National Cancer Centre Singapore. She obtained her MRCS (Member Royal College of Surgeon) in 2010 and FRCR (Fellow Royal College of Radiologist in clinical oncology) in 2016.
Work experience:
Dr Wong worked at the National Cancer Center of Singapore for more than 10 years before leaving for private practice. As part of her training in proton therapy, she received the Ministry of Health Manpower Development Program to spend time at St. Jude Children’s Research Hospital and observed at Provision Cares Proton Center, and Kobe Proton Center. She continues to serve the public as a visiting consultant in NCC Singapore and KK Hospital.
Specialised areas:
Her practice includes radiation therapy technology and the treatment of breast, head and neck, paediatric, brain, skin cancer and sarcoma. Dr Wong is skilled in the use of electrons, 3D, IGRT, VMAT, SBRT and Proton Beam Therapy in treating cancer.
Training courses:
She has attended relevant courses like Winter School in Particle Therapy, ESTRO Particle Therapy, ESTRO Radiobiology and physics, ESTRO brain, ESTRO Head and Neck, and ESTRO Stereotactic Radiosurgery.
Research:
Dr Wong was the principal investigator in a few clinical trials and studies while in public institutions.
Dr Wong has published local and regional papers on cancer prognostication, outcomes, and using novel techniques. Dr Wong concluded a clinical trial using hypo-fractionated radiotherapy in sarcomas. She also received grants to implement open-faced masks and silicon grip rings for patient comfort, electronic patient-reported outcomes, and study repeat MRI for adaptive radiotherapy in intracranial malignancies. While in National Cancer Center Singapore, she implemented new clinical technologies like pulsed low dose rate radiotherapy and collaborated with her colleagues to implement paediatric interstitial brachytherapy for rhabdomyosarcoma.
Dr Wong hopes to bring proton and advanced photon radiotherapy to Singapore and the region. Dr Wong is leveraging SAM network on the FLASH therapy consortium and A*STAR to investigate new technologies.
She published papers on multi-national outcomes of intra-cranial germ cell tumours, head and neck sarcomas, retroperitoneal sarcomas, brain tumours, proton beam therapy for whole-lung irradiation, dyspnea at the end of life, breast phyllodes tumours, breast cancer prognostication and breast cancer socio-demographics and mammogram screening patterns, Human Papilloma Virus vaccination knowledge, attitudes and practice amongst teenagers in Singapore etc.
See google scholar for more research publications.
Grants obtained:
- Duke-NUS Singhealth Academic Grant Proton Beam Therapy $50, 000 for short-course neoadjuvant radiotherapy in retroperitoneal liposarcomas with margins at risk.
- Onco-ACP Pediatric Research Grant Proton Beam Therapy $100,000 to utilise electronic patient reported outcomes.
- Duke-NUS Pediatric Cancer Charity Grant $40,000 to implement open-faced masks, silicon grip rings and investigate adaptive radiotherapy by repeating MRI for brain cancers.
Education:
Dr Wong was clinical teacher at Lee Kong Chian school of medicine, and clinical assistant professor at DUKE-NUS medical school. She also taught medical students and residents and continues to teach oncology nurses. She has organised various webinars and symposiums in the past for local and international faculty.
Memberships & Affiliates:
- Singapore Radiological Society (SRS)
- Royal College of Radiologists UK (FRCR)
- Southeast Asia Radiation Oncology Group (SEAROG)
- European Society Radiation Oncology ( ESTRO)
- Pediatric Radiation Oncology Society (PROS)
Awards & Honours:
Dean’s list 2009 NUS
ENT book prize, General surgery book prize
Human Manpower Development Program 2018
Long service award (10 years) Singhealth
Singhealth-Duke NUS Academic Research Grant 2021, 2022
Dr Shaun Ho Zhirui
Medical Director & Senior Consultant
Radiation Oncologist
Proton Therapy SG
Singapore Institute of Advanced Medicine
Visiting Consultant Radiation Oncologist
Raffles Cancer Centre, Raffles Hospital
Contact: shaun.ho@proton.sg
Biography:
Dr. Shaun Ho is an experienced senior radiation oncologist at Proton Therapy Singapore. He specialises in the use of advanced radiotherapy techniques to improve patient outcomes while minimizing treatment side effects. This encompasses proton beam therapy (PBT), stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS), as well as intensity modulated/volumetric modulated arc radiotherapy (IMRT/VMAT).
Prior to joining Proton Therapy Singapore, Dr. Ho was the head and Clinical Director of Radiation Oncology at Raffles Hospital. He also previously served as a Consultant and Clinical Assistant Professor at the National Cancer Centre Singapore (NCCS) and Duke-NUS Graduate Medical School.
Dr. Ho is an MOH accredited specialist in Radiation Oncology and a Fellow of the Academy of Medicine Singapore. He is also a Fellow of the UK Royal College of Radiologists (Clinical Oncology) and a Member of the Royal College of Surgeons of Edinburgh. Additionally, he holds a Graduate Diploma in Palliative Medicine.
He underwent radiation oncology residency at NCCS and subsequently completed a fellowship in Clinical Oncology at University College London Hospital (UCLH) in the UK. During his fellowship, he treated patients at UCH Macmillan Cancer Centre, the National Hospital for Neurology and Neurosurgery (NHNN), and was part of the London Sarcoma Service, one of the largest sarcoma services in Europe. His subspecialty training was in gastrointestinal oncology, neuro-oncology, sarcomas and lymphomas. He also underwent further training in proton beam therapy (PBT) at Kobe Proton Therapy Center in Japan, and at Taipei Medical University in Taiwan.
Dr. Ho served as a Consultant Radiation Oncologist at the National Cancer Centre Singapore (NCCS), specialising in gastrointestinal oncology, sarcomas, and lymphomas. During his time in public service, he received the SingHealth 10-year long service award in recognition of his contributions to patient care.
In 2020, Dr. Ho took on the role of Clinical Director of Radiation Oncology Services at Raffles Hospital. There, he established and operationalised their first radiotherapy services, which included techniques such as Stereotactic Body Radiotherapy (SBRT) for lung and bone tumours, Stereotactic Radiosurgery (SRS) for brain metastases, Deep Inspiratory Breath-hold (DIBH) Radiotherapy for breast cancer, and Volumetric Modulated Arc Therapy (VMAT) for cancers in the head and neck, lung, and prostate.
To advance the radiation oncology specialty in Singapore, Dr. Ho served on the Executive Committees of the Chapter of Radiation Oncologists, College of Radiologists Singapore, and the Singapore Radiological Society. He is also a member of the International Society for Radiosurgery.
Dr Ho treats patients for a wide range of conditions. He also has deep expertise and interest in the treatment of head & neck cancers, colorectal cancer, esophagus, liver and pancreatic cancers, lung cancer, breast cancer, , prostate cancer, sarcomas, lymphomas, and brain tumours.
Head & Consultant
Radiation Oncologist
Proton Therapy SG
Singapore Institute of Advanced Medicine
Visiting Consultant Radiation Oncologist
KK Women’s and Children’s Hospital, Singapore
Visiting Consultant Radiation Oncologist
National Cancer Centre Singapore
- Particle Therapy Cooperative Group (PTCOG) Genitourinary Subcommittee Member
- Children’s Oncology Group Member
- USA UFPTI Proton Fellowship-Trained
Conditions Treated:
- Paediatric- fellowship trained; Children’s Oncology Group Member Representative for NCCS
- Urologic- prostate and kidney
- Sarcomas
- Head and neck
- Liver cancer
Insurance Panels:
Main panel: HSBC Life (shield), Great Eastern, Income, Prudential
Extended panel: Singlife (pre-authorisation), AIA (pre-authoristion)
Appointments: +65 6708 7887 or email: frontdesk@proton.sg
Contact: WhatsApp +65 9297 5542 or email wenshen.looi@proton.sg.
Biography:
Dr Looi Wen Shen is a radiation oncologist at Proton Therapy SG, Singapore Institute of Advanced Medicine. He graduated from Yong Loo Lin School of Medicine, National University of Singapore in 2008, and went on to complete his residency training in National Cancer Centre Singapore (NCCS), before receiving specialist accreditation in radiation oncology by the Specialist Accreditation Board. He worked as a Consultant in the Division of Radiation Oncology, National Cancer Centre Singapore; Clinical Assistant Professor in Duke-NUS medical school; and Clinical Teacher in the Lee Kong Chian School of Medicine. During his time in public service in NCCS, Dr Looi oversaw the creation of a comprehensive paediatric radiation oncology program that integrated allied healthcare to improve patient satisfaction and experience. As an educator to the younger generation of doctors, Dr Looi obtained a certificate for Essential Skills in Medical Education (ESME) for this.
Dr Looi is a radiation oncologist with practical overseas experience in proton therapy, having practised at the University of Florida Proton Therapy Institute, USA, where he completed subspecialty fellowship training in proton therapy and paediatric radiotherapy as an Adjunct Clinical Post-Doctoral Associate. He also received further proton therapy training at the Taiwan Medical University Hospital Proton Centre for regionally endemic diseases such as liver cancer and nasopharyngeal cancer. He is adept at 3D conformal radiotherapy (3DCRT), intensity modulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), stereotactic body radiotherapy (SBRT), and intensity modulated proton therapy (IMPT).
Dr Looi is proud to have been able to kick start the paediatric proton program at National Cancer Centre Singapore. Today, Dr Looi continues to contribute to public healthcare as a Visiting Consultant in KK Women’s and Children’s Hospital and National Cancer Centre Singapore. Dr Looi is one of the few regional radiation oncologist members of the Children’s Oncology Group (COG). Additionally, he is listed in the Chordoma Foundation Directory (Wen Shen Looi). He is also a member of several other professional societies including the American Society for Radiation Oncology (ASTRO), Academy of Medicine, Singapore (AMS), Royal College of Radiology (RCR) (UK), Children’s Cancer and Leukaemia Group (CCLG) (UK), and the Paediatric Radiation Oncology Society (PROS).
While in NCCS, his research was published in journals such as the International Journal of Radiation Oncology Biology and Physics, and Medical Physics, Pediatric Blood and Cancer, and the Archives of Disease in Childhood. Through his research, Dr Looi endeavours to decrease the acute and late side effects of radiation in patients, thus improving their quality of life. Dr Looi will continue his research in the Singapore Institute of Advanced Medicine (SAM), focusing on the clinical outcomes of proton therapy. SAM’s plans for incorporation of FLASH proton therapy will also add an exciting dimension to the local proton research and clinical scene.
Publications:
Please see Google Scholar
Dr Brendan Chia is a Radiation Oncologist from Raffles Hospital.
In 2010, Dr Chia received his medical degree from the National University of Ireland, and subsequently underwent specialist training in radiation oncology at the National Cancer Centre Singapore. Concurrently, he also completed his Master of Clinical Investigation at the National University of Singapore. In 2016, he was elected as a Fellow of the Royal College of Radiologists, and received an award to undergo training in clinical oncology at St Bartholomew’s Hospital, London.
During his time in London, Dr Chia received training in CyberKnife, brachytherapy, general clinical oncology, as well as prostate, gynaecological, breast, and lung oncology. In 2023, Dr Chia was awarded a proton therapy fellowship. He underwent training for the use of proton therapy for a variety of cancers at the National Centre of Oncological Hadrontherapy in Italy, and the Shizuoka Cancer Centre in Japan.
Prior to joining Raffles Hospital, Dr Chia was a consultant at National Cancer Centre Singapore and was the radiation subsite lead for Neuro-oncology. He was also the Clinical Assistant Professor at Duke-NUS Graduate Medical School, and Principal Investigator for several clinical trials. As a keen educator, Dr Chia was actively involved in training medical students and doctors, and has presented at several international conferences. He is also a guest lecturer at Nanyang Polytechnic and Singapore Institute of Management for nursing and radiation therapy students.
Dr Chia serves on the Singapore Radiological Society’s executive committee, and is involved in the Leadership Development Program for the Federation of Asian Organisations for Radiation Oncology. He has also been awarded the SingHealth Gold Service Quality Award for consecutive years.
Dr Chia’s scope of practice is the use of radiotherapy to treat a variety of cancer patients. He is proficient in the use of advanced radiotherapy techniques such as proton therapy, stereotactic radiosurgery, stereotactic ablative body radiotherapy, and volumetric modulated arc therapy to improve patient outcomes, and minimise the side effects of treatment.
Education
FRCR Clinical Oncology (UK) 2016 - MCI (Singapore) 2016
- MB ChB BAO (Ireland) 2010
Professional Appointments and Committee Memberships
- Consultant. Department of Radiation Oncology, NCCS 2019 – present
- EXCO Member, Singapore Radiological Society 2017-present
- Member, Code Blue Committee, NCCS 2018-present
Awards
Masters of Clinical Investigation NMRC Sponsorship, 2013 - SingHealth Overseas Training Award 2016
Research Interests
Lung Radiotherapy - Biomarkers in Lung Cancer
- Brain Metastases Management
Publications
Thoracic intervention and surgery to cure lung: an overview of stereotactic ablative radiotherapy in early and oligometastatic lung cancer. J R Soc Med. 0(0) 1-7 2018 Jan 1:141076818763334. - Study protocol for the SARON trial: a multicentre,randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer. Conibear J, Chia B, Ngai Y, et al. BMJ Open. 2018 Apr 17;8(4):e020690.
- Pitfalls in lung stereotactic body radiotherapy—a review of organ toxicities and dose constraints. Chia B and Zubin M. J Xiangya Med 2018;3:36. doi: 10.21037/jxym.2018.09.04
Research Trials
- Treatment outcomes in Lung Radiotherapy
- CPAP use for Simulation in Radical Lung Radiotherapy
- Hippocampal Whole brain radiotherapy with or without Simultaneous intergrated boost in the management if multiple brain metastases.
Insurance Panels:
Shield Plan:
- HSBC Life
- Great Eastern,
- Income,
- Prudential
- Singlife (extended panel)
- AIA (extended panel)
Corporate Plan
- IHP
- MHC
- Fullerton FHN3
- Alliance